Publications

Publications Cover Photo

Scientific papers, book articles and patents

  • (69) Tiedemann, S; Stang, A; Last, S; Gefflaut, T; von Langermann, J.
    Preparative Enzymatic Synthesis of L-Homophenylalanine and α-Ketoglutarate with in situ-Product Crystallization
    >submitted (2024)
  • (68) Spang, J.; Bork, H.; Belov, F.; von Langermann, J.; Vorholt, A.; Gröger, H.
    One-pot aminoalkylation of alkenes under formation of primary amines by combining hydroformylation at 20 bar of syngas and biocatalytic transamination in water
    >Organic & Biomolecular Chemistry - accepted (2024)
  • (67) Heinks, T.; Hofmann, K.; Zimmermann, L.; Gamm, I.; Lieb, A.; Blach, L.; Wei, R.; Bornscheuer, U.T.; Thiele, J.; Hamel, C.; von Langermann, J.
    Comparative Biocatalytic Hydrolysis of PEF (Poly(ethylene furanoate)) with Various Esterases
    >submitted (2024)
  • (66) Behrens, J.; Tiedemann, S.; Kunde, T.; von Langermann, J.; Kienle, A.
    Moving Horizon Parameter Estimation for an Enzyme Catalyzed Transamination Reaction with Integrated Product Removal
    >Chemie Ingenieur Technik (2024)
  • (65) Heinks, T.; Hofmann, K.; Last, S.; Gamm, I.; Blach, L.; Wei, R.; Bornscheuer, U. T.; Hamel, C.; von Langermann, J.
    Selective Modification of the Product Profile of Biocatalytic Hydrolyzed PET via Product-specific Medium Engineering
    ChemRxiv (2024) - submitted
    > journal
  • (64) Behrens, J; Tiedemann, S.; von Langermann, J.; Kienle, A.
    Mathematical Modeling of an Enzyme Catalyzed Transamination Reaction with Integrated Product Removal
    Computer Aided Chemical Engineering (2024)
    > journal
  • (63) Belov, F; Gazizova, A.; Bork, H.; Gröger, H.; von Langermann, J.
    Crystallization assisted dynamic kinetic resolution for the synthesis of (R)-β-methylphenethylamine
    ChemBioChem, e202400203 (2024)
    > journal
  • (62) von Langermann, J., Kara, S.
    Principles of applied biocatalysis in K.-E. Jaeger, A. Liese & C. Syldatk (Editors) Introduction into Enzyme Technology (2024), Springer Nature, Heidelberg, USA
    > book
    > book chapter
  • (61) Tiedemann, S.; Neuburger, J. E.; Gazizova, A.; von Langermann, J.
    Continuous preparative application of amine transaminasecatalyzed reactions with integrated crystallization
    European Journal of Organic Chemistry, e202400068 (2024)
    > journal
  • (60) Terazzi, C.; Spannenberg, A.; von Langermann, J.; Werner, T.
    Chemoenzymatic Synthesis of Chiral Building Blocks Based on the Kinetic Resolution of Glycerol-Derived Cyclic Carbonates
    ChemCatChem, 15, e202300917 (2023)
    > journal
  • (59) Neuburger, J.E.; Gazizova, A.; Tiedemann, S.; von Langermann, J.
    Chemoenzymatic Synthesis of Enantiopure Amino Alcohols from Simple Methyl Ketones
    European Journal of Organic Chemistry, 26, e202201471 (2023)
    > journal
  • (58) Belov, F.; Mildner, A.; Knaus, T.; Mutti, F.; von Langermann, J.
    Crystallization-based downstream processing of ω-transaminase- and amine dehydrogenase-catalyzed reactions
    Reaction Chemistry & Engineering, 8, 1427-1439 (2023)
    > journal
  • (57) Neuburger, J.E.; Tiedemann, S.; Michalik, D., von Langermann, J.
    Development of a Rare Earth Element-based Recovery Concept for Cofactors from Aqueous Solutions
    Chemical Engineering & Technology, 46, 766-775 (2023)
    > journal
  • (56) Terazzi, T.; Laatz, K.; von Langermann, J.; Werner, T.
    Synthesis of Cyclic Carbonates Catalyzed by CaI2·Et3N and Studies on their Biocatalytic Kinetic Resolution
    ACS Sustainable Chemistry & Engineering, 10, 13335-13342 (2022)
    > journal
  • (55) Hahn, V.; Mikolasch, A.; Schmidt, M.; Neuburger J.E.; von Langermann, J.; Lalk, M.; Weltmann, K.-D.; von Woedtke, W.; Kolb, J.
    Hydroxylation and dimerization of para-dihydroxylated aromatic compounds mediated by cold atmospheric-pressure plasma in comparison with chemically catalyzed reactions
    Green Chemistry, 24, 7951-7967 (2022)
    > journal
  • (54) Belov, F.; Villinger, A.; von Langermann, J.
    (R)-Baclofen ((R)-4-Amino-3-(4-chlorophenyl)butanoic acid)
    Acta Crystallographica Section E, E78, 33-35 (2022)
    > journal (open access)
  • (53) Neuburger, J.; Tiedemann, S.; von Langermann, J.
    Verfahren zur Abtrennung eines Cofaktors aus einer Lösung
    (EN: Process for the recovery of a cofactor from a solution)
    Patent-Application DE 102021213181.6 (2021)
    (filed on November 23rd, 2021)
  • (52) Broese, T.; Ehlers, P.; Langer, P.; von Langermann, J.
    Chemoenzymatic Asymmetric Synthesis of Pyridine-based alpha-Fluorinated Secondary Alcohols.
    ChemBioChem, 22, 3314-3318 (2021)
    > journal (open access)
  • (51) Neuburger, J.; Helmholz, F.; Tiedemann, S.; Lehmann, P.; Süss, P.; Menyes, U.; von Langermann, J.
    Implementation and scale-up of a semi-continuous transaminase-catalyzed reactive crystallization for the preparation of (S)-(3-methoxyphenyl)ethylamine
    Chemical Engineering and Processing - Process Intensification, 168, 108578 (2021)
    > journal
  • (50) Hülsewede, D.; Neuburger, J.E.; von Langermann, J.
    Application of in situ-product crystallization in the amine transaminase from Silicibacter pomeroyi-catalyzed synthesis of (S)-1-(3-methoxyphenyl)ethylamine
    in J. Whittal & Peter W. Sutton (Editors) Applied Biocatalysis: The Chemist's Enzyme Toolbox (2020), John Wiley & Sons, Hoboken, New Jersey, USA
    > publisher
  • (49) von Langermann, J.; Hülsewede, D.; Tänzler, M.; Menyes, U.; Süss, P.
    Method for preparing amines from carbonyl compounds by transaminase reaction under salt precipitation
    EP-Patent: EP 3486324 B1 (filed on November 17th, 2017 and granted on June 10th, 2020)
    > Link DEPATISnet
    WO-Patent: WO 2019096973 A1 (filed on November 16th, 2018)
    > Link DEPATISnet
  • (48) Meyer, L.-E.; Brundiek, H.; von Langermann, J.
    Integration of Ion Exchange Resin Materials into Downstream-Processing of an Imine Reductase-Catalyzed Reaction
    Biotechnology Progress, 36, e3024 (2020)
    > journal (open access)
  • (47) Hülsewede, D.; Temmel, E.; Kumm, P.; von Langermann, J.
    Design of an integrated reactor-crystallizer process for the continuous biocatalytic synthesis of (S)-1-(3-Methoxyphenyl)ethylamine
    Crystals, 10, 345 (2020)
    > journal (open access)
  • (46) Kara, S.; von Langermann, J.
    Kompartimentierung bei den Enzymkaskaden: Statisch oder Durchfluss
    Biospektrum, 02, 215-217 (2020)
    > journal (open access)
  • (45) Meyer, L.-E.; Gummesson, A.; Kragl, U.; von Langermann, J.
    Development of Ionic Liquid-Water-Based Thermomorphic Solvent (TMS)-Systems for Biocatalytic Reactions
    Biotechnology Journal, 14, 1900215 (2019)
    > journal
  • (44) Hülsewede, D.; Dohm, J.-N.; von Langermann, J.
    Donor amine salt-based continuous in situ-product crystallization in amine transaminase-catalyzed reactions
    Advanced Synthesis & Catalysis, 361, 2727-2733 (2019)
    > journal (open access)
  • (43) Hülsewede, D.1; Meyer, L.-E.1; von Langermann, J.
    (1Both authors have contributed equally.)
    Application of in situ-Product Crystallization and Related Techniques in Biocatalytic Processes
    Chemistry - A European Journal, 25, 4871-4884 (2019)
    > journal
    Frontispiece: > link
  • (42) Uhrich, D.; Jang, H.-Y.; Park, J.-B.; von Langermann, J.
    Characterization and application of resistant polyurethane-based enzyme and whole cell compartments
    Journal of Biotechnology, 289, 31-38 (2019)
    > journal
  • (41) Meissner, M. P.; Süss, P.; Brundiek, H.; Woodley, J.; von Langermann, J.
    Scoping the Enantioselective Desymmetrization of a Poorly Water-Soluble Diester by Recombinant Pig Liver Esterase
    Organic Process Research & Development, 22, 1518-1523 (2018)
    > journal
  • (40) Kara, S.; von Langermann, J.
    Prinizipien der angewandten Biokatalyse
    in Liese, A.; Jaeger, K.-E.; Syldatk, C. (Eds.) Einführung in die Enzymtechnologie (2018), chapter 13, Springer-Verlag GmbH, Berlin
    > link
  • (39) Meyer, L.-E.; Plasch, K.; Kragl, U.; von Langermann, J.
    Adsorbent-based downstream-processing of the decarboxylase-based synthesis of 2,6-dihydroxy-4-methylbenzoic acid
    Organic Process Research & Development, 22, 963-970 (2018)
    > journal
  • (38) Meyer, L.-E.; von Langermann, J.; Kragl, U.
    Recent developments in biocatalysis in multiphasic ionic liquid reaction systems
    Biophysical Reviews, 10, 901-910 (2018)
    > journal
  • (37) Hülsewede, D.; Tänzler, M.; Süss, P.; Mildner, A.; Menyes, U.; von Langermann, J.
    Development of an in situ-Product Crystallization (ISPC)-Concept to Shift the Reaction Equilibria of Selected Amine Transaminase-Catalyzed Reactions
    European Journal of Organic Chemistry, 18, 2130-2133 (2018)
    > journal
  • (36) Uhrich, D.; von Langermann, J.
    Preparation and Characterization of Enzyme Compartments in UV-cured Polyurethane-based Materials and their Application in Enzymatic Reactions
    Frontiers in Microbiology, 8, 2111 (2017)
    > journal (open access)
  • (35) Bracco, P.; Busch, H.; von Langermann, J.; Hanefeld, U.
    Enantioselective synthesis of cyanohydrins catalysed by hydroxynitrile lyases - a review
    Organic & Biomolecular Chemisty, 14, 6375-6389 (2016)
    > journal
  • (34) Hinze, J.; Süss, P.; Strohmaier, S.; Bornscheuer, U.T.; Wardenga, R.; von Langermann, J.
    Recombinant pig liver esterase-catalyzed synthesis of (1S,4R)-4-hydroxy-2-cyclopentenyl acetate combined with subsequent enantioselective crystallization
    Organic Process Research & Development, 20, 1258-1264 (2016)
    > journal
  • (33) Süss, P.; Borchert, S.; Hinze, J.; Illner, S.; von Langermann, J.; Kragl, U.; Wardenga, R.; Bornscheuer, U.
    Chemoenzymatic sequential one-pot reaction for the synthesis of (1R,2S)-1-(methoxycarbonyl)cyclohex-4-ene-2-carboxylic acid with recombinant pig liver esterase
    Organic Process Research & Development, 19, 2034-2038 (2015)
    > journal
  • (32) von Langermann, J.; Temmel, E.; Seidel-Morgenstern, A.; Lorenz, A.
    Solid Phase Behavior in the Chiral Systems of Various 2-Hydroxy-2-phenylacetic Acid (Mandelic Acid) Derivatives
    Journal of Chemical & Engineering Data, 60, 721-728 (2015)
    > journal
  • (31) von Langermann, J.; Wapenhensch, S.
    Hydroxynitrile lyase-catalyzed Synthesis of Enantiopure Cyanohydrins in Biocatalytic Active Static Emulsions (BASE) with Suppression of the Non-enzymatic Side Reaction
    Advanced Synthesis and Catalysis, 14-15, 2989–2997 (2014)
    > journal
    appeared also as front cover picture of Adv. Synth. Catal. issue 14-15/2014
    > journal
  • (30) Plagemann, R.; von Langermann, J.; Kragl, U.
    Microwave assisted covalent immobilization of enzymes on inorganic surfaces
    Engineering in Life Sciences, 14, 493-499 (2014)
    > journal (open access)
  • (29) von Langermann, J.; Nedrud, D.M.; Kazlauskas, R.J.
    Increasing the reaction rate of hydroxynitrile lyase from Hevea brasiliensis towards mandelonitrile by copying active site residues from an esterase that accepts aromatic esters
    ChemBioChem, 15, 1931-1938 (2014)
    > journal
  • (28) Hering, C.; von Langermann, J.; Schulz, A.
    The Elusive Cyanoformate – An Unusual Cyanide Shuttle
    Angewandte Chemie-International Edition, 53, 8282-8284 (2014)
    > journal
    Das schwer fassbare Cyanformiat: ein ungewöhnlicher Cyanidtransporter
    Angewandte Chemie, 126, 8422-8424 (2014)
    > journal
  • (27) Sistla, V.S.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A.
    Occurrence and consequences of differences in the cation/anion ratios during classical resolution: D-/L-serine benzyl ester 2,3-toluyl-D-tartrate
    Crystal Research & Technology, 7, 514-520 (2014)
    > journal
  • (26) Süss, P.; Illner, S.; von Langermann, J.; Borchert, S.; Bornscheuer, U.T.; Wardenga, R.; Kragl, U.
    Scale-up of a Recombinant Pig Liver Esterase-Catalyzed Desymmetrization of Dimethyl Cyclohex-4-en-cis-1,2-dicarboxylate
    Organic Process Research & Development, 18, 897−903 (2014)
    > journal
  • (25) Diebler, J.; von Langermann, J.; Mell, A.; Hein, M.; Langer, P.; Kragl, U.
    Synthesis of Aliphatic and α-Halogenated Ketone Cyanohydrins with the
    Hydroxynitrile Lyase from Manihot esculenta
    ChemCatChem, 6, 987-991 (2014)
    > journal
  • (24) von Langermann, J.; Kaspereit, M.; Mozaffar, S.; Lorenz, H.; Hedberg, M.; Jones, M.J.; Larson, K.; Herrschend, B.; Arnell, R.; Temmel, E.; Bäckvall, J.-E.;Kienle, A.; Seidel-Morgenstern, A.
    Design of an Integrated Process of Chromatography, Crystallization and Racemization for the Resolution of 2 ́,6 ́-Pipecoloxylidide (PPX)
    Organic Process Research and Development, 16, 343-352 (2012)
    > journal
  • (23) Sistla, V.S.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A.
    Analysis and Comparison of Commonly Used Acidic Resolving Agents in Diastereomeric Salt Resolution - Examples for DL-Serine
    Crystal Growth & Design, 11, 3761-3768 (2011)
    > journal
  • (22) Lorenz, H.; von Langermann, J.; Sadiq, G.; Seaton, C.C.; Davey, R.J.; Seidel-Morgenstern, A.
    The phase behaviour and crystallisation of 2-chloromandelic acid: the crystal structure of the pure enantiomer and the existence of a metastable conglomerate
    Crystal Growth & Design, 11, 1549-1556 (2011)
    > journal
  • (21) Tulashie, S.K.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A.
    Chiral Task-Specific Solvents for Mandelic Acid and their Impact on Solution Thermodynamics and Crystallization Kinetics
    Crystal Growth & Design, 11, 240-246 (2011)
    > journal
  • (20) Le Minh, T.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A.
    Enantiomeric 3-Chloromandelic Acid System: Binary Melting Point Phase Diagram, Ternary Solubility Phase Diagrams and Polymorphism
    Journal of Pharmaceutical Sciences, 99, 4084-4095 (2010)
    > journal
  • (19) Enthaler, S.; von Langermann, J.; Schmidt, T.
    Carbon Dioxide and Formic Acid – The couple for an environmental friendly hydrogen storage?
    Energy & Environmental Science, 3, 1207-1217 (2010)
    > journal
  • (18) Sistla, V.S.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A.
    Application of classical Resolution for separation of DL-serine
    Chemical Engineering and Technology, 33, 780-786 (2010)
    > journal
  • (17) von Langermann, J.; Lorenz, H.; Boehm, O.; Flemming, A.; Bernsdorf, A.; Köckerling, M.; Schinzer, A.; Seidel-Morgenstern; A.
    6,7-Dimethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g] isochinolin-5-yl)-3H-2-benzofuran-1-one (alpha-Noscapine)
    Acta Crystallographica Section E, 66, O570 (2010)
    > journal (open access)
  • (16) von Langermann, J.; Le Minh, T.; Lorenz, H.; Seidel-Morgenstern, A.
    Kombination von Biokatalyse und Kristallisation zur Darstellung enantiomerenreiner Mandelsäurederivate (Combination of biocatalysis and crystallisation to represent enantiopure mandelic acid derivatives)
    Chemie Ingenieur Technik, 82, 93-100 (2010)
    > journal
  • (15) Andexer, J.N.; von Langermann, J.; Kragl, U.; Pohl, M.
    How to overcome limitations in biotechnological processes - examples from hydroxynitrile lyase applications
    Trends in Biotechnology, 27, 599-607 (2009)
    > journal
  • (14) von Langermann, J.; Mell, A.; Paetzold, E.; Kragl, U.
    Hydroxynitrile lyase catalysed synthesis of enantiopure (S)-acetophenone cyanohydrins
    in J. Whittal & Peter W. Sutton (Editors) Practical Methods in Biocatalysis and Biotransformations (2009), John Wiley & Sons Ltd, Chichester, 262-265
    > publisher
  • (13) Le Minh, T.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A.
    Using isothermal and polythermal methods to investigate ternary diagrams of 3-Chloromandelic acid system in water and toluene
    Journal of Science and Technology, 47, 56-62 (2009)
  • (12) Guterl, J.-K.; Andexer, J.N.; Sehl, T.; von Langermann, J.; Frindi-Wosch, I.; Rosenkranz, T.; Fitter, J.; Gruber, K.; Kragl, U.; Eggert, T.; Pohl, M.
    Uneven Twins: Comparison of two Hydroxynitrile Lyases with α/β-Hydrolase Fold
    Journal of Biotechnology, 141, 166-173 (2009)
    > journal
  • (11) von Langermann, J.; Guterl, J.-K.; Pohl, M.; Wajant, H.; Kragl, U.
    Hydroxynitrile lyase catalyzed cyanohydrin synthesis at high pH-values
    Bioprocess and Biosystems Engineering, 31, 155-161 (2008)
    > journal
  • (10) Andexer, J.; von Langermann, J.; Mell, A.; Bocola, M.; Kragl, U.; Eggert, T.; Pohl, M.
    A new (R)-selective Hydroxynitrile Lyase from Arabidopsis thaliana with an α/β-Hydrolase fold.
    Angewandte Chemie-International Edition, 46, 8679-8681 (2007)
    > journal
    Angewandte Chemie, 45, 8833-8835 (2007)
    > journal
  • (9) von Langermann, J.; Mell, A.; Paetzold, E; Daußmann, T; Kragl, U.
    Hydroxynitrile lyase in organic solvent free systems to overcome thermodynamic limitations
    Advanced Synthesis and Catalysis, 349, 1418-1424 (2007)
    > journal
  • (8) Dreyer, S.; Lembrecht, J.; Schumacher, J.; Kragl, U.
    Enzyme catalysis in non-aqueous media - past-present-future
    in R. Patel (Ed.) Biocatalysis in the Pharmaceutical and Biotechnology Industries (2006), CRC-Press, Taylor & Francis Group, Boca Raton, 791-828
    > publisher
  • (7) Eckstein, M.F.; Lembrecht, J.; Schumacher, J.; Eberhard, W.; Spiess, A.; Peters, M.; Roosen, C.; Greiner, L.; Leitner, W.; Kragl, U.
    Maximise your equilibrium conversion in biphasic catalysed reactions: How to obtain reliable data for equilibrium constants?
    Advanced Synthesis and Catalysis, 348, 1597-1604 (2006)
    > journal
  • (6) Schumacher, J.; Eckstein, M.; Kragl, U.
    Influence of water-miscible organic solvents on kinetics and enantioselectivitiy of the (R)-specific alcohol dehydrogenase from Lactobacillus brevis
    Biotechnology Journal, 1, 574-581 (2006)
    > journal

proceedings (only >5 pages)

  • (5) Behrens J., Tiedemann S., von Langermann J., Kienle A.
    Mathematical modeling of an enzyme catalyzed transamination reaction with integrated product removal
    in Proceedings of the 34th European Symposium on Computer Aided Process Engineering / 15th International Symposium on Process Systems Engineering (ESCAPE34/PSE24), 2024, Florence, Italy
    > publisher
  • (4) Tulashie, S.K.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A.
    Chiral Tailor-Made Solvents and Their Impact on Solution Thermodynamics and Crystallisation Kinetics of Mandelic Acid
    in Proceedings of the 17th International Workshop on Industrial crystallization (BIWIC 2010), Halle, Germany, 42-48
    > publisher
  • (3) Sistla, V.S.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A.
    Application of different acidic resolving agents for diastereomeric salt separation of serine
    in Proceedings of the 17th International Workshop on Industrial crystallization (BIWIC 2010), Halle, Germany, 490-494
    > publisher
  • (2) Sistla, V.S.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A.
    Phase diagrams of diastereomeric salts and their application
    in BIWIC 2009, 16th International Workshop on Industrial Crystallization (2009), Eds: M. Louhi-Kultanen and H. Hatakka; Lappeenranta University of Technology, Finland
  • (1) Le Minh, T.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A.
    Using isothermal and polythermal methods to investigate ternary solubility phase diagrams of 3-chloromandelic acid system in water and toluene
    in Proceedings of the 11th Conference on Science and Technology (2009), Ho Chi Minh City, Vietnam, 795-801

 

Conference Cover Photo Publications

Conference Contributions


oral presentations

  • (61) Neuburger, J.; Tiedemann, S.; Belov, F.; von Langermann, J.
    Design of a (Semi‑)continuously Operated Transaminase-Catalyzed Reaction Using in situ-Product Crystallization
    Biocat 2022, Hamburg, Germany
    28.8.-1.9.2022
  • (60) von Langermann, J.
    Crystallization-based process intensification of biocatalytic reactions
    Intensifying Biocatalytic Processes, IBPRO 2022, Bielefeld, Germany
    28.-30.3.2022
  • (59) von Langermann, J.
    Integrated use of selective separation processes in biocatalytic reactions
    MECP 2020+1 - Multistep Enzyme Catalyzed Processes, Aachen, Germany (online)
    13.-16.9.2021
  • (58) Neuburger, J.E.; Helmholz, F.; Tiedemann, S.; Lehmann, P.; Süss, P.; Menyes, U.; von Langermann, J.
    Integrated application and scale-up of a selective in situ-product crystallization in an amine transaminase-catalyzed reaction
    2nd Japan-Switzerland-Germany Workshop on Biocatalysis and Bioprocess Development, Ascona, Switzerland (online)
    6.-9.9.2021
  • (57) Neuburger, J.E.; Hülsewede, D.; Belov, F.; Süss, P.; Menyes, U.; von Langermann, J.
    Integrated application and scale-up of a selective crystallization in an enzyme-catalysed synthesis process
    ISIC 21 - 21st International Symposium on Industrial Crystallization, Potsdam, Germany (online)
    30.8.-2.9.2021
  • (56) von Langermann, J.
    Integration of Separation Techniques into Biocatalytic Reactions
    CATALOX Seminar, Graz, Austria (online)
    18.5.2021
  • (55) von Langermann, J.
    Integration of Separation Techniques into Biocatalytic Synthesis Processes for the Preparation of Enantiopure Compounds
    54. Jahrestreffen Deutscher Katalytiker, Weimar, Germany (online)
    16.-19.3.2021
  • (54) von Langermann, J.
    Integration of Crystallization into Biocatalytic Synthesis Processes
    Bayer Science Lunch, Leverkusen, Germany (online)
    27.1.2021
  • (53) Hülsewede, D.; Neuburger, J.E.; Meyer, L.-E.; Mildner, A.; Cornelius, M.; von Langermann, J.
    Integration of Crystallization into Biocatalytic Synthesis Processes for the Efficient Synthesis of Valuable Compounds
    Jahrestreffens der ProcessNet-Fachgruppe Kristallisation 2020, Dortmund, Germany (online)
    10.7.2020
  • (52) Uhrich, D.; Meyer, L.-E.; Jang, H.-Y.; Hülsewede, D.; Neuburger, M.; von Langermann, J.
    Integration of Separation Techniques into Biocatalytic Processes
    Seminar of the Applied Biocatalysis Group at Biochemical Engineering, TU Berlin, Berlin, Germany (online)
    6.5.2020
  • (51) Hülsewede, D.; Neuburger, J.E.; Meyer, L.-E.; von Langermann, J.
    Development of an integrated crystallization-transaminase process for the continuous synthesis of chiral amines
    4th Indo-German workshop on  “Advances in Materials, Reactions & Separation Processes, Berlin, Germany
    24.-26.2.2020
  • (50) Hülsewede, D.; Kumm, P.; von Langermann, J.
    Application of a donor amine salt for the in situ-product crystallization in amine transaminase catalyzed reactions
    Amine Biocatalysis 4.0 conference, Stuttgart, Germany
    17.-19.2.2020
  • (49) Uhrich, D.; Meyer, L.-E.; Jang, H.-Y.; Hülsewede, D.; Neuburger, J.; Tänzler, M.; von Langermann, J.
    Integration of Separation Techniques into Biocatalytic Processes for the Synthesis of Enantiopure Compounds
    Protein Engineering Congress EU, Frankfurt, Germany
    12.-13.11.2019
  • (48) Meyer, L.-E.; Gumesson, A.; Grollmisch, A.; Claus, J.; von Langermann, J.; Kragl, U.
    Ionic liquid-water-based thermomorphic solvent systems for enzymatic synthesis of fine chemicals
    1st Japan-Germany-Switzerland Workshop for Enzyme Technology and Bioprocess Development, Toyama, Japan
    10.-12.09.2019
  • (47) Hülsewede, D.; Neuburger J.E.; Meyer, L.-E., von Langermann, J.
    Using in situ-product crystallization (ISPC) to shift the reaction equilibria of selected transaminase-catalyzed reactions
    1st Japan-Germany-Switzerland Workshop for Enzyme Technology and Bioprocess Development, Toyama, Japan
    10.-12.9.2019
  • (46) Meyer, L.-E.; Gummesson, A.; von Langermann, J.; Kragl, U.
    Ionic Liquid-Water-Based Thermomorphic Solvent Systems for Enzymatic Synthesis of Fine Chemicals
    14th European Congress on Catalysis (EuropaCat 2019), Aachen, Germany,
    18.08.–23.08.2019
  • (45) von Langermann, J.
    Compartmentalization in biocatalysis for the synthesis of enantiopure compounds
    LIKAT Seminar at Leibniz-Institut für Katalyse e.V.,Rostock, Deutschland
    18.7.2019
  • (44) von Langermann, J.
    Integration of Separation Techniques into Biocatalytic Processes for the Synthesis of Enantiopure Compounds
    Hanse Chemistry Symposium 2019, Rostock, Germany
    16.-17.5.2019
  • (43) von Langermann, J.
    Efficient P-based organocatalysts and biocatalysts for the resolution of racemic carbonates
    P-Campus-Symposium, Rostock, Germany
    26.4.2019
  • (42) Meyer, L.-E.; Hülsewede, D.; von Langermann, J.
    Integration of adsorption and crystallization into biocatalytic synthesis to overcome process limitations
    Young Professionals Conference on Process Engineering (YCOPE 2019), Magdeburg, Germany
    18.-20.3.2019
  • (41) Hülsewede, D.; Dohm, J.-N.; von Langermann, J.
    Verwendung eines Donoramin-Salzes für die in situ-Produktkristallisation aus einer Amintransaminase-katalysierten Reaktion
    Jahrestreffen der ProcessNet-Fachgruppen Zerkleinern und Klassieren, Kristallisation und Grenzflächenbestimmte Systeme und Prozesse, Bamberg, Germany
    12.-13.3.2019
  • (40)von Langermann, J.
    Crystallization of valuable phosphate-based cofactors from biocatalytic applications
    P-Campus Symposium, Dummerstorf, Germany
    19.-20.11.2019
  • (39) Hülswede, D.; Süss, P.; Menyes, U.; von Langermann, J.
    Development of an in situ-Product Crystallization (ISPC) to Shift the Reaction Equilibria of Selected Transaminase-Catalyzed Reactions
    ProcessNet-Jahrestagung und 33. DECHEMA-Jahrestagung der Biotechnologen 2018, Aachen, Germany
    10.-13.9.2018
    see also: Chemie Ingenieur Technik, 90, 1259-1260 (2018)
    > journal
  • (38) von Langermann, J.
    Integration of separation techniques into biocatalytic processes for the synthesis of enantiopure compounds
    Sondervortrag, OCI-Kolloquium, Universität Bielefeld, Bielefeld, Germany
    16.7.2018
  • (37) Hülsewede, D.; Uhrich, D.; Meyer, L.-E.; von Langermann, J.
    Improving biocatalysis by combining catalysis and separation processes
    8th International CeBiTec Research Conference and the 1st BIOCASCADES Symposium 'Reaction Concepts for Industrial Biocatalysis', Bielefeld, Germany
    9.-11.4.2018
  • (36) Hülsewede, D.; Tänzler, M.; Süss, P.; Mildner, A.; Menyes, U.; von Langermann, J.
    Gleichgewichtsverschiebung einer biokatalytischen Aminierungsreaktion durch in situ-Produktkristallisation
    Jahrestreffen der ProcessNet-Fachgruppe Kristallisation, Bremen, Germany
    8.-9.3.2018
  • (35) Uhrich, D.; Hülsewede, D.; Meyer, L. von Langermann, J.
    Synthesis of enantiopure compounds by combining biocatalysis and separation processes
    Chemiedozententagung 2018, Jena, Germany
    5.-7.3.2018
  • (34) Hülsewede, D.; Tänzler, M.; Süss, P.; Mildner, A.; Menyes, U.; von Langermann, J.
    Equilibrium displacement by in situ-product crystallisation (ISPC) intransaminase-catalysed reactions
    Amine Biocat 3.0, Manchester, United Kingdom
    11.-13.12.2017
  • (33) Uhrich, D.; von Langermann, J.
    Polyurethane-based compartmentalization of biocatalysts
    19th Japanese-German Workshop on Enzyme Technology 2017, Rostock, Germany
    21-22.9.2017
  • (32) von Langermann, J.
    A) Compartmentalization of biocatalystspart; B) in situ product removal techniques in biocatalysis; part C) Biocatalysis and selective crystallization for the preparation of enantiopure compounds
    Seminar at Ewha Womens University, Seoul, South Korea
    5.1.2017
  • (31) Süss, P.; Sehl, T.; Gyollai, V.; von Langermann, J.; Wardenga, R.
    Putting the Bottle on the Table” – Process Development of Chemo-biocatalytic Reactions at Enzymicals
    8th International Congress on Biocatalysis 2016 (Biocat 2016), Hamburg, Germany
    28.8.-1.9.2016
  • (30) Hinze, J.; Süss, P.; Bornscheuer, U.; Wardenga, R.; Kragl, U.; von Langermann, J.
    Scale-up of Recombinant Pig Liver Esterase-catalyzed Reactions
    49. Jahrestreffen Deutscher Katalytiker, Weimar, Germany
    16.-18.3.2016
  • (29) von Langermann, J.; Uhrich, D.; Peinemann, J.; Wapenhensch, S.
    Application of Biocatalytic Cascade Reaction with Contrary Reaction Specifications
    ESCRE 2015, European Symposium on Reaction Engineering, Fürstenfeldbruck, Germany
    27.-30.10.2015
  • (28) von Langermann, J.
    Biobased economy - current and future process concepts
    12th Japanese-German Frontiers of Science Symposium, Kyoto, Japan
    1.-4.10.2015
  • (27) Wapenhensch, S.; Uhrich, D.; Peinemann, J.C.; von Langermann, J.
    Kompartmentierung von Biokatalysatoren für den Einsatz in Kaskadenreaktionen
    24. Nachwuchswissenschaftlersymposium Bioorganik, Hamburg, Germany
    23.-25.9.2015
  • (26) Uhrich, D.; Peinemann, J.C.; Wapenhensch, S.; von Langermann, J.
    Compartmentation of contrary biocatalytic reaction zones for the use in cascade reactions
    18th Japanese-German Workshop Enzyme Technology, Kyoto, Japan
    13.-15.9.2015
  • (25) Gummesson, A.; von Langermann, J.; Kragl, U.
    Biocatalysis in Thermomorphic Systems
    Joint EMLG/JMLG Annual Meeting 2015, Rostock, Germany
    6.-10.09.2015
  • (24) Gummesson, A.; Kragl, U.; von Langermann, J.
    Biocatalysis in thermomorphic solvents
    ProcessNet Jahrestagung und 31. DECHEMA-Jahrestagung der Biotechnologen 2014, Aachen, Germany
    30.9.-2.10.2014
    see also: Chemie Ingenieur Technik, 86, 1523 (2014)
    > journal
  • (23) von Langermann, J.; Wapenhensch, S.
    Hydroxynitrile lyase-catalyzed Synthesis of Enantiopure Cyanohydrins in Biocatalytic Active Static Emulsions (BASE)
    7th International Congress on Biocatalysis 2014 (Biocat 2014), Hamburg, Germany
    31.8.-4.9.2014
  • (22) Süss, P.; Illner, S.; von Langermann, J.; Borchert, S.; Bornscheuer, U.; Wardenga, R.; Kragl, U.
    Scale-up of a Recombinant Pig Liver Esterase-Catalyzed Desymmetrization of Dimethyl Cyclohex-4-ene-cis-1,2-dicarboxylate
    7th International Congress on Biocatalysis 2014 (Biocat 2014), Hamburg, Germany
    31.8.-4.9.2014
  • (21) von Langermann, J.
    Hydroxynitrile lyases in non-conventional media
    Bionoco Summer School, Aachen, Germany
    9.-11.9.2013
  • (20) von Langermann, J.; Zhang, Z.-J; Xu, J.-H.; Dean, A.; Kazlauskas, R.
    Using ancestral enzyme concepts to improve biocatalysts
    Biotrans 2013, Manchester, UK
    20.-25.7.2013
  • (19) Romas Kazlauskas, Zhi-Jun Zhang, Bryan Jones, Jan von Langermann
    Reconstruction of catalytically promiscuous ancestral enzymes as catalysts for unnatural reactions
    245th ACS National Meeting & Exposition, New Orleans, USA
    7.-11.4.2013
  • (18) von Langermann, J.; Zhang, Z.-J. ; Nedrud, D.M.; Kazlauskas, R. Modifikation der Hydroxynitrillyase aus Hevea brasiliensis zur Verbesserung unnatürlicher Reaktionen
    21. Nachwuchswissenschaftler-Symposium Bioorganische Chemie 2012, Rostock, Germany
    3.-5.9.2012
  • (17) von Langermann, J.; Lorenz, H.; Kaspereit, M.; Hedberg, M.; Jones, M. J.; Herschend, B.; Larson, K.; Shakeri, M.; Bäckvall, J.-E.; Kienle, A.; Seidel-Morgenstern, A. Crystallization-based Integrated Process for the Resolution of a Pharmaceutically Relevant Intermediate
    AIChE 2011 Annual Meeting, Minneapolis, USA
    16.-21.10.2011
  • (16) Sistla, S.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A. Systematic approach for chiral separation via diastereomeric salt formation
    AIChE 2011 Annual Meeting, Minneapolis, USA
    16.-21.10.2011
  • (15) Kaspereit, M.; von Langermann, J.; Swernath, S.; García Palacios, J.; Lorenz, H.; Hedberg, M.; Seidel-Morgenstern, A.; Kienle, A. Integrated Processes for the Production of Pure Enantiomers
    8th European Congress of Chemical Engineering, Berlin, Germany
    25.-29.9.2011
  • (14) Petrychkovych, P.; von Langermann J.; Setnickova, K.; Uchytil, P. The influence of water on butanols isomers pervaporation transport through polyethylene membrane
    21st Annual Meeting of the North American Membrane Society, Las Vegas, USA
    4.-8.6.2011
  • (13) Larson, K.; von Langermann, J.
    Separation of two AstraZeneca-Compounds and Noscapine
    Workshop - Integrated chemical synthesis and product purification, Berlin, Germany
    12.-13.5.2011
  • (12) von Langermann, J.; Lorenz H.; Seidel-Morgenstern, A.Mandelic Acid Derivatives - Asymmetric Synthesis and Solid Phase Behaviour
    AstraZeneca Chemical Sciences-lecture, Södertälje, Sweden
    18.11.2010
  • (11) Sistla, S.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A. Application of different acidic resolving agents for diastereomeric salt separation of serine
    BIWIC 2010, 17th International Workshop on Industrial Crystallization, Halle, Germany
    8.-10.9.2010
  • (10) von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A. Metastable Conglomerates of Mandelic Acid Derivatives - Potentials and Limitations
    2010 Annual Conference of the British Association for Crystal Growth (BACG 2010), Manchester, United Kingdom
    5.-7.9.2010
  • (9) von Langermann, J.; Andexer, J. N.; Kragl, U.; Pohl, M.; Seidel-Morgenstern, A. Hydroxynitrile Lyases - Synthetic Applications and Limitations
    EuchemMS, Chemistry Congress Nürnberg 2010, Nürnberg, Germany
    29.8.-2.9.2010
  • (8) von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A. Mandelic Acid (Derivatives)–Asymmetric Synthesis, Solid Phase Behaviour and Crystallisation
    ISCD–22, 22nd International Symposium on Chirality (Chirality 2010), Sapporo, Japan
    12.-15.7.2010
  • (7) von Langermann, J.; Kaspereit, M.; Lorenz, H.; Kienle, A.; Seidel-Morgenstern, A. Darstellung einer pharmazeutisch relevanten Verbindung über einen integrierten Prozess aus Chromatographie und Kristallisation
    Processnet, Jahrestreffen des Fachausschusses Kristallisation, Magdeburg, Germany
    11.-12.3.2010
  • (6) Le Minh, T.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A. Using isothermal and polythermal methods to investigate ternary solubility phase diagrams of 3-chloromandelic acid system in water and toluene
    11th Conference on Science and Technology, Ho Chi Minh City, Vietnam
    21.-23.10.2009
  • (5) von Langermann, J.; Le Minh, T.; Lorenz, H.; Seidel-Morgenstern, A. Kombination von Biokatalyse und Kristallisation zur Darstellung enantiomerenreiner Verbindungen
    Processnet-Jahrestagung / Jahrestagung der Biotechnologen, Mannheim, Germany
    8.-10.9.2009
    see also: Chemie Ingenieur Technik, 81, 1254 (2009)
    > journal
  • (4) von Langermann, J.; Kragl, U.
    Total suppression of the non-enzymatic reaction in hydroxynitrile lyase catalysed cyanohydrin synthesis
    BioNoCo-Lecture, Forschungszentrum Jülich, Germany
    22.1.2009
  • (3) von Langermann, J.; Kragl, U.
    Total suppression of the non-enzymatic reaction in hydroxynitrile lyase catalysed cyanohydrin synthesis
    European Bioperspectives 2008, Hannover, Germany
    7.-9.10.2008
  • (2) von Langermann, J.; Kragl, U.
    Biokatalyse mit Hydroxynitril Lyasen - Unterdrückung der nicht-enzymatischen Cyanhydrinsynthese
    41. Jahrestreffen Deutscher Katalytiker, Weimar, Germany
    27.-29.2.2008
  • (1) Kragl, U.; Arndt, C.; Eckstein, M.; Horn, A.; Pilz, R.; Schumacher, J.
    Hohe Temperaturen, Lösungsmittel und Mehrphasensysteme - Neue Trends und Verfahren der Enzymkatalyse
    Dechema / GVC-Jahrestagung 2004, Karlsruhe, Germany
    12.-14.10.2004

 poster presentations

  • (70) Neuburger, J.; Tiedemann, S.; von Langermann, J.
    Development of a Recovery Concept for Phosphate-based Cofactors from Aqueous Reaction Media
    Biocat 2022, Hamburg, Germany
    28.8.-1.9.2022
  • (69) Terrazzi, C.; Laatz, K.C.; von Langermann, J.; Werner, T.
    Cyclic Carbonates Synthesis Catalyzed by CaI2·Et3N
    55. Jahrestreffen Deutscher Katalytiker, Weimar, Germany
    27.-29.6.2022
  • (68) Tiedemann, S.*; Neuburger, J.E.; von Langermann, J.
    Preparative implementation of in situ-product crystallization in semi-continuous amine-transaminase-catalyzed reactions
    Intensifying Biocatalytic Processes, IBPRO 2022, Bielefeld, Germany
    *S.T. received a Poster Award
  • (67) Belov, F.; von Langermann, J.
    Investigation of (R)-Baclofen kinetic resolution and crystallization potentials
    Intensifying Biocatalytic Processes, IBPRO 2022, Bielefeld, Germany
  • (66) Neuburger, J.E.; Hülsewede, J.; Belov, F.; von Langermann, J.
    Development of a suspension-to-suspension process concept in a (semi-)continuously operated transaminase-catalyzed reaction system
    13th European Congress of Chemical Engineering and 6th European Congress of Applied Biotechnology (ECCE & ECAB 2021), Berlin, Germany (online)
    (appeared also a Poster FlashTalk)
  • (65) Meyer, L.-E.; von Langermann, J.
    Utilization of ion exchange resins in downstream-processing concepts of imine reductase- and decarboxylase-catalyzed reactions
    MECP 2020+1 - Multistep Enzyme Catalyzed Processes, Aachen, Germany (online)
  • (64) Neuburger, J.; Süss, P.; Menyes, U.; von Langermann, J.
    Use of a suspension-to-suspension reaction concept in a (semi-) continuously operated enzymatic reaction-crystallization system
    Biotrans 2021, Graz, Austria (online)
  • (63) Belov, F.; von Langermann, J.
    Investigation of the chymotrypsin-catalyzed kinetic resolution of baclofen
    Biotrans 2021, Graz, Austria (online)
  • (62) Terazzi, C.; Werner, T.; von Langermann, J.
    Pig liver esterase-catalyzed kinetic resolution of cyclic carbonates
    Biotrans 2021, Graz, Austria (online)
  • (61) Meyer, L.-E.; von Langermann, J.
    Utilization of ion exchange resins in downstream-processing concepts of imine reductase- and decarboxylase-catalyzed reactions
    Biotrans 2021, Graz, Austria (online)
  • (60) Hülsewede, D.; Neuburger, J.; Süss, P.; Helmholz, F.; Menyes, U.; von Langermann, J.
    Implementation and scale-up of in situ-product crystallization concepts in transaminase-catalyzed reactions
    Biotrans 2021, Graz, Austria (online)
  • (59) Neuburger, J.E.; Süss, P.; Menyes, U.; von Langermann, J.
    Use of a suspension-to-suspension reaction in a continuously operated transaminase-reaction system
    Jahrestreffen der ProcessNet-Fachgruppe Kristallisation 2021, Karlsruhe, Germany (online)
    18.-19.3.2021
  • (58) Leipold, F.; Süss, P.; Hülsewede, D.; Neuburger, J.; von Langermann, J.
    An in situ-Product Crystallization Concept to Shift the Reaction Equilibria of Selected Amine Transaminase-Catalyzed Reactions
    Amine Biocatalysis 4.0 conference, Stuttgart, Germany
    17.-19.2.2020
  • (57) Meyer, L.-E.; Werner, T.; von Langermann, J.
    Application of phosphorous-based solutions in biocatalysis
    P-Campus Symposium, Warnemünde, Germany
    12.-13.11.2019
  • (56) Meyer, L.-E.; Plasch, K.; Glueck, S.M.; Faber, K.; Kragl, U.; von Langermann, J.
    Adsorbent-based downstream-processing of a decarboxylase-based synthesis of 2,6-dihydroxy-4-methylbenzoic acid
    Young Professionals Conference on Process Engineering (YCOPE 2019), Magdeburg, Germany
    18.-20.3.2019
  • (55) Hülswede, D.; Süss, P.; Menyes, U.; von Langermann, J.*
    Development of an in situ-product crystallization (ISPC)-concept to shift the reaction equilibria of selected transaminase-catalyzed reactions
    9th International Congress on Biocatalysis, Hamburg, Germany
    26.-30.8.2018
    *J.v.L. received a Biocat Poster Award 2018
  • (54) Hülsewede, D.; Dohm, J.; von Langermann, J.
    Coupled two reactor-concept for an in situ-product crystallization in transaminase-catalyzed reactions
    9th International Congress on Biocatalysis, Hamburg, Germany
    26.-30.8.2018
  • (53) Meyer, L.-E.; Plasch, K.; Glueck, S.M.; Faber, K.; Kragl, U.; von Langermann, J.
    Adsorbent-based downstream-processing of a decarboxylase-based synthesis of 2,6-dihydroxy-4-methylbenzoic acid
    9th International Congress on Biocatalysis, Hamburg, Germany
    26.-30.8.2018
  • (52) Hülsewede, D.; Dohm, J.-N.; von Langermann, J.
    Coupled two reactor-concept for an in situ-product crystallization in transaminase-catalyzed reactions
    8. Innovationskongress Chemie und Biotechnologie, Magdeburg, Germany
    30.5.2018
  • (51) Meyer, L.-E.; Plasch, K.; Glueck, S.; Kragl, U.; Faber, K.; von Langermann, J.
    Adsorbent-based downstream-processing of a decarboxylase-based synthesis of 2,6-dihydroxy-4-methylbenzoic acid
    8. Innovationskongress Chemie und Biotechnologie, Magdeburg, Germany
    30.5.2018
  • (50) Hinze, J.; Strohmaier, S.; Süß, P.; Borchert, S.; Bornscheuer, U.T.; Wardenga, R.; von Langermann, J.
    Recombinant pig liver esterase-catalyzed synthesis of (1R,4S)-4-Hydroxy-2-cyclopentenyl acetate with subsequent enantioselective crystallization
    8. Innovationskongress Chemie und Biotechnologie, Magdeburg, Germany
    30.5.2018
  • (49) Hülsewede, D.; Dohm, J.-N.; von Langermann, J.
    Coupled two reactor-concept for an in situ-product crystallization in transaminase-catalyzed reactions
    JungChemikerForum Rostock (JCF Rostock) Posterparty 2018, Rostock, Germany
    11.4.2018
  • (48) Meyer, L.-E.*; Plasch, K.; Glueck, S.; Kragl, U.; Faber, K.; von Langermann, J.
    Adsorbent-based downstream-processing of a decarboxylase-based synthesis of 2,6-dihydroxy-4-methylbenzoic acid
    JungChemikerForum Rostock (JCF Rostock) Posterparty 2018, Rostock, Germany
    11.4.2018
    *L.-E. M. received a JCF Poster Award 2018
  • (47) Hülsewede, D.; Dohm, J.-N.; von Langermann, J.
    Coupled two reactor-concept for an in situ-product crystallization in transaminase-catalyzed reactions
    8th Int. CeBiTec Research Conference, Bielefeld, Germany
    9.-11.4.2018
  • (46) Uhrich, D.; Jang, H.-Y-; Park, J.-B.; von Langermann, J.
    Preparation and characterization of biocatalyst compartments in UV-cured polyurethane-based materials and their application in biotransformations
    19th Japanese-German Workshop on Enzyme Technology, Rostock, Germany
    21.-22.9.2017
  • (45) Gummesson, A.; Meyer, L.-E.; von Langermann, J.
    Ionic liquid-based thermomorphic solvent systems for biocatalytic reactions
    19th Japanese-German Workshop on Enzyme Technology, Rostock, Germany
    21.-22.9.2017
  • (44) Meyer, L.-E.; Plasch, K.; Peinemann, J.C.; Glück, S; Kragl, U.; Faber, K.; von Langermann, J.
    In situ product removal (ISPR) by selective crystallization in biocatalytic carboxylation reactions
    19th Japanese-German Workshop on Enzyme Technology, Rostock, Germany
    21.-22.9.2017
  • (43) Tänzler, M.; Menyes, U.; Brundiek, H.; von Langermann, J.; Kragl, U.
    Process development of the (R)-selective transamination of 3-acetylpyridine
    Biotrans 2017, Budpest, Hungary
    9.-13.7.2017
  • (42) Gummesson, A.; Meyer, L.-E.; von Langermann, J.
    Ionic liquid-based thermomorphic solvent systems for biocatalytic reactions
    Biotrans 2017, Budpest, Hungary
    9.-13.7.2017
  • (41) Meyer, L.-E.; Plasch, K.; Peinemann, J.C.; Glück, S; Kragl, U.; Faber, K.; von Langermann, J.
    In situ product removal (ISPR) by selective crystallization in biocatalytic carboxylation reactions
    Biotrans 2017, Budpest, Hungary
    9.-13.7.2017
  • (40) Uhrich, D.; Jang, H.-Y-; Park, J.-B.; von Langermann, J.
    Preparation and characterization of biocatalyst compartments in UV-cured polyurethane-based materials and their application in biotransformations
    5th International Conference on Biocatalysis in Non-Conventional Media, Rostock, Germany 9.-11.5.2017
  • (39) Gummesson, A.; Meyer, L.-E.; von Langermann, J.
    Ionic liquid-based thermomorphic solvent systems for biocatalytic reactions
    5th International Conference on Biocatalysis in Non-Conventional Media, Rostock, Germany 9.-11.5.2017
  • (38) Meyer, L.-E.; Plasch, K.; Peinemann, J.C.; Glück, S; Kragl, U.; Faber, K.; von Langermann, J.
    In situ product removal (ISPR) by selective crystallization in biocatalytic carboxylation reactions
    5th International Conference on Biocatalysis in Non-Conventional Media, Rostock, Germany
    9.-11.5.2017
  • (37) Peinemann, J.C.; Plasch, K.; Meyer, L.-E.; Glueck, S.; Kragl, U.; Faber, K.; von Langermann, J.
    Use of Selective Crystallization as an in situ Product Removal Technique Biocatalytic Carboxylation Reactions
    European Summit of Industrial Biotechnology (ESIB 2016), Graz, Austria
    14.-16.11.2016
  • (36) Hinze, J.; Strohmaier, S.; Süss, P.; Borchert, S.; Bornscheuer, U.; Wardenga, R.; von Langermann, J.
    Recombinant Pig Liver Esterase-catalyzed Synthesis of (1R,4S)-4-hydroxy-2-cyclopentenyl Acetate with Subsequent Enantioselective Crystallisation
    8th International Congress on Biocatalysis 2016 (Biocat 2016), Hamburg, Germany
    28.8.-1.9.2016
  • (35) Meyer, L.-E.; Gummesson, A.; von Langermann, J.
    Ionic Liquid-based Thermomorphic Solvent Systems for Biocatalytic Reactions
    8th International Congress on Biocatalysis 2016 (Biocat 2016), Hamburg, Germany
    28.8.-1.9.2016
  • (34) Wapenhensch, S.; von Langermann, J.
    Biocatalytic Cascade Reactions with Contrary Reaction Conditions in Biphasic Systems
    8th International Congress on Biocatalysis 2016 (Biocat 2016), Hamburg, Germany
    28.8.-1.9.2016
  • (33) Broese, T.; Ehlers, P.; Langer, P.; von Langermann, J.
    Alcohol Dehydrogenase-catalyzed Enantioselective Synthesis of α-Halogenated Alcohols Bearing a Pyridine Ring
    8th International Congress on Biocatalysis 2016 (Biocat 2016), Hamburg, Germany
    28.8.-1.9.2016
  • (32) Uhrich, D.; Peinemann, J.C.; Wapenhensch, S.; von Langermann, J.
    Artificial cell like compartments for enzyme catalysis
    12th Japanese-German Frontiers of Science Symposium, Kyoto, Japan
    1.-4.10.2015
  • (31) Gummesson, A.; von Langermann, J.; Kragl, U.
    Biocatalysis in thermomorphic solvents
    ECCE 10 + ECAB 3 + EPIC 5, Nice, France
    27.09.-01.10.2015
  • (30) Süss, P.; Hinze, J.; Illner, S.; von Langermann, J.; Borchert, S.; Bornscheuer, U.; Wardenga, R.; Kragl, U.
    Synthesis of fine chemicals with Recombinant Pig Liver Esterases - from screening to scale-up
    ECCE 10 + ECAB 3 + EPIC 5, Nice, France
    27.09.-01.10.2015
  • (29) Gummesson, A.; von Langermann, J.; Kragl, U.
    Biocatalysis in Thermomorphic Systems
    Joint EMLG/JMLG Annual Meeting 2015, Rostock, Germany
    6.-10.09.2015
  • (28) Hinze, J.; Strohmaier, S.; Süss, P.; Borchert, S.; Bornscheuer, U.T.; Wardenga, R.; Kragl, U.; von Langermann, J.
    Recombinant pig liver esterase-catalyzed synthesis of (1S, 4R)-4-Hydroxy-2-cyclopentenyl acetate with subsequent enantioselective crystallisation
    Biotrans 2015, Vienna, Austria
    26.-30.07.2015
  • (27) Uhrich, D.; Peinemann, J.C.; Wapenhensch, S.; von Langermann, J.
    A compartmented biocatalytic cascade reaction with contrary reaction conditions
    Biotrans 2015, Vienna, Austria
    26.-30.07.2015
  • (26)von Langermann, J.; Nedrud, D.M.; Kazlauskas, R.J.
    Increasing the reaction rate of hydroxynitrile lyase from Hevea brasiliensis towards mandelonitrile
    ProcessNet Jahrestagung und 31. DECHEMA-Jahrestagung der Biotechnologen 2014, Aachen, Germany
    30.9.-2.10.2014
    see also: Chemie Ingenieur Technik, 86, 1419 (2014)
    > journal
  • (25)von Langermann, J.; Wapenhensch, S.
    Hydroxynitrile lyase-catalyzed Synthesis of Enantiopure Cyanohydrins in Biocatalytic Active Static Emulsion (BASE)
    ProcessNet Jahrestagung und 31. DECHEMA-Jahrestagung der Biotechnologen 2014, Aachen, Germany
    30.9.-2.10.2014
    see also: Chemie Ingenieur Technik, 86, 1418 (2014)
    > journal
  • (24) Süss, P.; Illner, S.; von Langermann, J.; Borchert, S.; Bornscheuer, U.; Wardenga, R.; Kragl, U.
    Synthesis of fine chemicals with recombinant isoforms of pig liver esterase
    7th International Congress on Biocatalysis 2014 (Biocat 2014), Hamburg, Germany
    31.8.-4.9.2014
  • (23) Diebler, J.; von Langermann, J.; Mell, A.; Hein, M.; Langer, P.; Kragl, U.
    Biocatalytic Synthesis of Aliphatic and α-Halogenated Ketone Cyanohydrins with the Hydroxynitrile Lyase from Manihot esculenta
    7th International Congress on Biocatalysis 2014 (Biocat 2014), Hamburg, Germany
    31.8.-4.9.2014
  • (22) Wilhelm, S.; Dreyer, S.; von Langermann, J.; Kragl, U.
    Stabilizing Effects of an Ionic Liquid on the Alcohol dehydrogenase from Lactobacillus brevis
    Bionoco Summer School, Aachen, Germany
    9.-11.9.2013
  • (21)von Langermann, J.; Zhang, Z.-J.; Tan, M. A. O.; Kazlauskas, R.
    Protein Engineering of the Hydroxynitrile lyase from Hevea brasiliensis (HbHNL) to Improve the Unnatural Nitroaldol-Reaction
    BTI Showcase/Industry Interaction meeting, Saint Paul, USA
    29.11.2012
  • (20)von Langermann, J.; Lorenz, H.; Jones, M.; Hedberg, M.; Seidel-Morgenstern, A. Solid Phase Behaviour of 2,6-Pipecoloxilidide
    18th International Symposium on Industrial Crystallization, Zürich, Switzerland
    13.-16.9.2011
  • (19) Horvath, Z.; Temmel, E.; Lee, J. W.; von Langermann, J.; Kaspereit, M.; Kaemmerer, H.; Seidel-Morgenstern, A. Chromatographic Separation of two AstraZeneca-Compounds and Noscapine
    Workshop - Integrated chemical synthesis and product purification, Berlin, Germany
    12.-13.5.2011
  • (18)von Langermann, J.; Le Minh, T.; Taratin, N.; Lorenz, H.; Seidel-Morgenstern, A. Crystallization and Phase Diagrams of Mandelic Acid Derivatives
    Workshop-Integrated chemical synthesis and product purification, Berlin, Germany
    12.-13.5.2011
  • (17)von Langermann, J.; Kaemmerer, H.; Lorenz, H.; Seidel-Morgenstern, A. Crystallisation Behaviour of 2 AstraZeneca-Compounds
    Workshop - Integrated chemical synthesis and product purification, Berlin, Germany 12.-13.5.2011
  • (16)von Langermann, J.; Lorenz H.; Seidel-Morgenstern, A.Derivate der Mandelsäure-Untersuchungen zu kristallisationsrelevanten physikochemische Eigenschaften
    Processnet - Jahrestreffen des Fachausschusses Kristallisation, Bad Dürkheim, Germany
    24.-25.2.2011
  • (15) Wong Lee, J.; Horvath, Z.; Shitov, S.; von Langermann, J.; Böhm, O.; Schinzer, D.; Seidel-Morgenstern, A. Comparisons of Batch Chromatography and Simulated Moving Bed Process for the Separation of Noscapine Enantiomers
    Spica 2010, 13th Symposium on Preparative and Industrial Chromatography and Allied Techniques, Stockholm, Sweden
    8.-10.9.2010
  • (14) Tulashie, S.K.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A. Chiral Tailor-Made Solvents and Their Impact on Solution Thermodynamics and Crystallisation Kinetics of Mandelic Acid
    BIWIC 2010, 17th International Workshop on Industrial Crystallization, Halle, Germany
    8.-10.9.2010
  • (13) Sadiq, G.; Davey, R.; Lorenz, H.; von Langermann, J.
    API Crystallisation- Conglomerate or compound
    9th International Workshop on Crystal Growth of Organic Materials (CGOM9), Singapore
    4.-7.8.2010
  • (12) Le Minh, T.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A. Solid-Liquid Equilibria (SLE) in the enantiomeric 3-chloromandelic acid system
    Annual meeting of the Technical committee crystallisation, Magdeburg, Germany
    11.-12.3.2010
  • (11)von Langermann, J.; Le Minh, T.; Lorenz, H.; Seidel-Morgenstern, A. Biokatalytische Synthese von Cyanhydrinen und deren Potential für die Darstellung enantiomerenreiner Verbindungen
    18. Nachwuchswissenschaftler-Symposium Bioorganische Chemie, Hannover, Germany
    28.-30.9.2009
  • (10) Sistla, V.S.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A. Phase diagrams of diastereomeric salts and their application
    BIWIC 2009, 16th International Workshop on Industrial Crystallization, Lappeenranta, Finland
    9.-11.9.2009
  • (9) Sistla, V.S.; von Langermann, J.; Lorenz, H.; Seidel-Morgenstern, A. Diastereomeric resolution of DL-serine–systematic approach via phase diagrams
    Annual meeting of the Technical committee crystallisation, Dortmund, Germany
    12.-13.3.2009
  • (8) Lorenz, H.; von Langermann, J.; Kaemmerer, H.; Seidel-Morgenstern, A. INTENANT-A European collaboration project : Integrated synthesis & purification of single enantiomers
    BIWIC 2008, Magdeburg, Germany
    10.-12.9.2008
  • (7) Andexer, J. N.; Guterl, J.-K.; von Langermann, J.; Mell, A.; Eggert, T.; Kragl, U; Pohl, M.
    The first R-selective Hydroxynitrile lyase with an α/β-Hydrolase fold
    New Directions in Molecular Genetics and Genomics, Freiburg, Germany
    9.-11.4.2008
  • (6)von Langermann, J.; Kragl, U.
    Hydroxynitrile lyases in organic solvent free systems to overcome thermodynamic limitations
    10. Frühjahrssymposium der Jungchemiker, Rostock, Germany 27.-29.3.2008
  • (5) Mell, A.; Andexer, J.; von Langermann, J.; Kragl, U.
    A new (R)-selective Hydroxynitrile lyase from Arabidopsis thaliana
    10. Frühjahrssymposium der Jungchemiker, Rostock, Germany
    27.-29.3.2008
  • (4)Schumacher, J.; Kragl, U.
    Oxynitrilases in organic free systems to overcome thermodynamic limitations
    Biocat - International Congress on Biocatalysis, Hamburg, Germany 3.-7.9.2006
  • (3)Schumacher, J.; Eckstein, M.; Kragl, U.
    Influence of water-miscible organic solvents on a secondary alcohol dehydrogenase from Lactobacillus brevis
    7th International Symposium on Catalysis Applied to Fine Chemicals, Bingen/Mainz, Germany 23.-27.10.2005
  • (2)Schumacher, J.; Eckstein, M.; Kragl, U.
    Influence of water-miscible organic solvents on a secondary alcohol dehydrogenase from Lactobacillus brevis
    Bioperspectives 2005, Wiesbaden, Germany
    10.-12.5.2005
  • (1)Schumacher, J.; Vogl, C.; Kragl, U.
    Arbeitsgruppe Technische Chemie
    ConNeCat-Partnering Event – Katalytische Verfahren zur Nutzung nachwachsender Rohstoffe, Frankfurt am Main, Germany
    25.1.2005

(* - 2007: Jan Schumacher; 2007 - today: Jan von Langermann)

Letzte Änderung: 27.10.2024 - Ansprechpartner: Webmaster